Enzymatic Properties of the Unnatural β-l-Enantiomers of 2‘,3‘-Dideoxyadenosine and 2‘,3‘-Didehydro-2‘,3‘-dideoxyadenosine-Reference-Cited by-同舟云学术

Enzymatic Properties of the Unnatural β-l-Enantiomers of 2‘,3‘-Dideoxyadenosine and 2‘,3‘-Didehydro-2‘,3‘-dideoxyadenosine

Published:1997-11-01 Issue:24 Volume:40 Page:3969-3973
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pélicano Hélène¹,Pierra Claire¹,Eriksson Staffan¹,Gosselin Gilles¹,Imbach Jean-Louis¹,Maury Georges¹

Affiliation:

1. Laboratoire de Chimie Bioorganique, UMR 5626 du CNRS, Département de Chimie Organique Fine, Université Montpellier-2 des Sciences et Techniques du Languedoc, 34095 Montpellier Cedex 5, France, and Department of Veterinary Medical Chemistry, Swedish University of Agricultural Sciences, Biomedical Centre, Box 575, S-751 23 Uppsala, Sweden

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9701482

Reference29 articles.

1. Resolution of racemic carbocyclic analogs of purine nucleosides through the action of adenosine deaminase. Antiviral activity of the carbocyclic 2'-deoxyguanosine enantiomers

2. Enzymatic production of optically pure (2′R-cis)-2′-deoxy-3′-thiacytidine (3TC, lamivudine): A potent anti-HIV agent

3. New approaches to the synthesis of antiviral nucleosides

4. The Effect of Absolute Configuration on the Anti-HIV and Anti-HBV Activity of Nucleoside Analogues

5. Anti-human immunodeficiency virus activities of the beta-L enantiomer of 2',3'-dideoxycytidine and its 5-fluoro derivative in vitro

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