Pyridone Methylsulfone Hydroxamate LpxC Inhibitors for the Treatment of Serious Gram-Negative Infections-Reference-Cited by-同舟云学术

Pyridone Methylsulfone Hydroxamate LpxC Inhibitors for the Treatment of Serious Gram-Negative Infections

Published:2012-02-08 Issue:4 Volume:55 Page:1662-1670
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Montgomery Justin I.¹,Brown Matthew F.¹,Reilly Usa¹,Price Loren M.¹,Abramite Joseph A.¹,Arcari Joel¹,Barham Rose¹,Che Ye¹,Chen Jinshan Michael¹,Chung Seung Won¹,Collantes Elizabeth M.¹,Desbonnet Charlene¹,Doroski Matthew¹,Doty Jonathan¹,Engtrakul Juntyma J.¹,Harris Thomas M.¹,Huband Michael¹,Knafels John D.¹,Leach Karen L.¹,Liu Shenping¹,Marfat Anthony¹,McAllister Laura¹,McElroy Eric¹,Menard Carol A.¹,Mitton-Fry Mark¹,Mullins Lisa¹,Noe Mark C.¹,O’Donnell John¹,Oliver Robert¹,Penzien Joseph¹,Plummer Mark¹,Shanmugasundaram Veerabahu¹,Thoma Christy¹,Tomaras Andrew P.¹,Uccello Daniel P.¹,Vaz Alfin¹,Wishka Donn G.¹

Affiliation:

1. Worldwide Medicinal Chemistry, ‡Computational Chemistry, §Antibacterials Research Unit, ∥Drug Metabolism, ⊥Structural Biology, #Primary Pharmacology, Pfizer Worldwide Research and Development, 445 Eastern Point Road, Groton, Connecticut 06340, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2014875

Reference31 articles.

1. Fix the antibiotics pipeline

2. Federal Funding for the Study of Antimicrobial Resistance in Nosocomial Pathogens: No ESKAPE

3. Progress and Challenges in Implementing the Research on ESKAPE Pathogens

4. Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

5. Mechanism and Inhibition of LpxC: An Essential Zinc-Dependent Deacetylase of Bacterial Lipid A Synthesis

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