Benzodiazepine Receptor Ligands. 4. Synthesis and Pharmacological Evaluation of 3-Heteroaryl-8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-Oxides-Reference-Cited by-同舟云学术

Benzodiazepine Receptor Ligands. 4. Synthesis and Pharmacological Evaluation of 3-Heteroaryl-8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-Oxides

Published:1999-06-01 Issue:12 Volume:42 Page:2218-2226
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Costanzo Annarella¹,Guerrini Gabriella¹,Ciciani Giovanna¹,Bruni Fabrizio¹,Selleri Silvia¹,Costa Barbara¹,Martini Claudia¹,Lucacchini Antonio¹,Aiello Petra Malmberg¹,Ipponi Alessandra¹

Affiliation:

1. Dipartimento di Scienze Farmaceutiche, Università degli Studi di Firenze, Via Gino Capponi 9, 50121 Firenze, Italy, Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, Università degli Studi di Pisa, Via Bonanno 6, 56126 Pisa, Italy, and Dipartimento di Farmacologia Preclinica e Clinica Aiazzi-Mancini, Università degli Studi di Firenze, Viale Pieraccini 6, 50139 Firenze, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm981126y

Reference26 articles.

1. Reactivity of 1-(2-nitrophenyl)-5-aminopyrazoles under basic conditions and synthesis of new 3-, 7-, and 8-substituted pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides, as benzodiazepine receptor ligands

2. Benzodiazepine receptor ligands. Synthesis and pharmacological evaluation of 3-, 7- and 8-substituted [5,1-c][1,2,4]benzotriazines and 5-oxide derivatives. Part I

3. Benzodiazepine receptor ligands — Part II. Synthesis and biological evaluation of pyrazolo[5,1-c][1,2,4]benzotriazine 4-oxide

4. 2-(Oxadiazolyl)- and 2-(thiazolyl)imidazo[1,2-a]pyrimidines as agonists and inverse agonists at benzodiazepine receptors

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