The Vinylfluoro Group as an Acetonyl Cation Equivalent: Stereoselective Synthesis of 6-Substituted 4-Hydroxy Pipecolic Acid Derivatives
Author:
Affiliation:
1. Organisch-Chemisches Institut, Universität Münster, Corrensstrasse 40, D-48149 Münster, Germany
2. International NRW Graduate School of Chemistry (GSC-MS), Universität Münster, Corrensstrasse 36, D-48149 Münster, Germany
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo901872a
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1. Substitution of proline with pipecolic acid at the scissile bond converts a peptide substrate of HIV proteinase into a selective inhibitor
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4. Epoxide derivatives of pipecolic acid and proline are inhibitors of pipecolate oxidase
5. Asymmetric synthesis of cis-(−)-(2R4S)-4-(phosphonomethyl)-2-piperidinecarboxylic acid, a potent NMDA receptor antagonist
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