Soluble 2-Substituted Aminopyrido[2,3-d]pyrimidin-7-yl Ureas. Structure−Activity Relationships against Selected Tyrosine Kinases and Exploration of in Vitro and in Vivo Anticancer Activity
Author:
Affiliation:
1. Departments of Chemistry, Cancer Research, and Vascular and Cardiac Diseases, Pfizer Global Research & Development, Ann Arbor Laboratories, 2800 Plymouth Road, Ann Arbor, Michigan 48105
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm0004291
Reference52 articles.
1. Tyrosine Kinase Inhibition: An Approach to Drug Development
2. Protein tyrosine kinase inhibitors in cancer treatment
3. Receptor tyrosine kinases as targets for inhibition of angiogenesis
4. Angiogenesis in cancer, vascular, rheumatoid and other disease
Cited by 57 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Novel tetrahydronaphthalen-1-yl-phenethyl ureas: synthesis and dual antibacterial-anticancer activities;Journal of Enzyme Inhibition and Medicinal Chemistry;2023-12-07
2. A straightforward synthesis of potentially biologically active novel urea derivatives from 1,2,3,4-tetrahydronaphthalene-2-carboxylic acids;Monatshefte für Chemie - Chemical Monthly;2022-09-26
3. A Review on Fused Pyrimidine Systems as EGFR Inhibitors and Their Structure–Activity Relationship;Frontiers in Chemistry;2022-06-13
4. Substituted Tetrahydronaphthalen‐1‐yl‐phenethyl Ureas: Synthesis, Characterization, and Biological Evaluations;ChemistrySelect;2022-04-19
5. Novel naphthalene-1,5-diamine containing urea/thiourea derivatives – Promising antimicrobial agents;Organic Communications;2021-12-30
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3