Total Synthesis of AMF-26, an Antitumor Agent for Inhibition of the Golgi System, Targeting ADP-Ribosylation Factor 1-Reference-Cited by-同舟云学术

Total Synthesis of AMF-26, an Antitumor Agent for Inhibition of the Golgi System, Targeting ADP-Ribosylation Factor 1

Published:2012-12-28 Issue:1 Volume:56 Page:150-159
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shiina Isamu¹,Umezaki Yuma¹,Ohashi Yoshimi²,Yamazaki Yuta¹,Dan Shingo²,Yamori Takao²

Affiliation:

1. Department of Applied Chemistry, Faculty of Science, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan

2. Division of Molecular Pharmacology, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo 135-8550, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm301695c

Reference46 articles.

1. Yamada, N.WO2005/070856, 2005, Nippon Shinyaku Co., Ltd.

2. AMF-26, a Novel Inhibitor of the Golgi System, Targeting ADP-ribosylation Factor 1 (Arf1) with Potential for Cancer Therapy

3. Reaching for high-hanging fruit in drug discovery at protein–protein interfaces

4. Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor

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