Synthesis and Evaluation of a Series of C3-Substituted CBI Analogues of CC-1065 and the Duocarmycins-Reference-Cited by-同舟云学术

Synthesis and Evaluation of a Series of C3-Substituted CBI Analogues of CC-1065 and the Duocarmycins

Published:2001-06-28 Issue:15 Volume:66 Page:5163-5173
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Boger Dale L.¹,Brunette Steven R.¹,Garbaccio Robert M.¹

Affiliation:

1. Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo010309g

Reference29 articles.

1. CC-1065 (NSC-298223), a new antitumor antibiotic. Production, in vitro biological activity, microbiological assays and taxonomy of the producing microorganism.

2. Duocarmycins, Potent Antitumor Antibiotics Produced by Streptomyces sp. Structures and Chemistry.

3. Duocarmycin SA, a new antitumor antibiotic from Streptomyces sp.

4. Pyrindamycins A and B, new antitumor antibiotics.

5. CC-1065 and the duocarmycins: unraveling the keys to a new class of naturally derived DNA alkylating agents.

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