Cholesterol-Dependent Macropinocytosis and Endosomal Escape Control the Transfection Efficiency of Lipoplexes in CHO Living Cells-Reference-Cited by-同舟云学术

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Cholesterol-Dependent Macropinocytosis and Endosomal Escape Control the Transfection Efficiency of Lipoplexes in CHO Living Cells

Published:2012-01-09 Issue:2 Volume:9 Page:334-340
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Cardarelli Francesco¹,Pozzi Daniela²,Bifone Angelo¹,Marchini Cristina³,Caracciolo Giulio²

Affiliation:

1. Center for Nanotechnology Innovation @NEST, Istituto Italiano di Tecnologia, Piazza San Silvestro 12, 56127 Pisa, Italy

2. Department of Molecular Medicine, “Sapienza” University of Rome, Viale Regina Elena, 324, 00161, Rome, Italy

3. Department of Bioscience and Biotechnology, University of Camerino, Via Gentile III da Varano, 62032 Camerino (MC), Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp200374e

Reference31 articles.

1. Cationic liposome-mediated transfection

2. The influence of size, lipid composition and bilayer fluidity of cationic liposomes on the transfection efficiency of nanolipoplexes

3. Toward the Rational Design of Lipid Gene Vectors: Shape Coupling between Lipoplex and Anionic Cellular Lipids Controls the Phase Evolution of Lipoplexes and the Efficiency of DNA Release

4. Formation and Intracellular Trafficking of Lipoplexes and Polyplexes

5. Intracellular trafficking of nonviral vectors

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