Using Potassium Carbonate to Scavenge Hydrogen Fluoride: A Scale-Up Process for Quantitative Production of (1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-(oxo-κO)-3-quinolinecarboxylato-κO3)difluoro−Boron
Author:
Affiliation:
1. Johnson & Johnson Pharmaceutical Research & Development, L.L.C., East Coast Research & Early Development, 1000 Route 202, Raritan, New Jersey 08869, U.S.A.
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op8000228
Reference23 articles.
1. CLINICAL USE OF THE FLUOROQUINOLONES
2. Comparative Pharmacokinetics and Pharmacodynamics of the Newer Fluoroquinolone Antibacterials
3. Emerging Mechanisms of Fluoroquinolone Resistance
4. synthesis and antibacterial activities of optically active ofloxacin and its fluoromethyl derivative.
5. Structural identification and characterization of impurities in moxifloxacin
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