Practical Asymmetric Synthesis of Trifluoromethyl-Containing Aminoester Using a Modified Davis Protocol-Reference-Cited by-同舟云学术

Practical Asymmetric Synthesis of Trifluoromethyl-Containing Aminoester Using a Modified Davis Protocol

Published:2008-05-01 Issue:3 Volume:12 Page:424-428
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Alimardanov Asaf¹,Schmid Jean¹,Afragola Jay¹,Khafizova Gulnaz¹

Affiliation:

1. Wyeth Research, 401 North Middletown Road, Pearl River, New York 10965, U.S.A.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op700259d

Reference25 articles.

1. aKreft, A. F., Resnick, L., Mayer, S. C. Diamantidis, G., Cole, D. C., Harrison, B. L., Zhang, M., Hoke, M., Ting, W., and Galante, R. C. U.S. Patent20040198778, 2004; Chem. Abstr. 2004, 141, 314147

2. Asymmetric synthesis of novel α-amino acids with β-branched side chains

3. Estimated 80% ee.

4. Preparation of Bis(trifluoromethyl) Compounds via Functionalization of 1,1,1,3,3,5,5,5-Octafluoropentane

5. bVan Der Puy, M.U.S. Patent6,072,088;Chem. Abstr. 2000, 130, 15138.

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