Scale-Up Synthesis of a TRPV1 Antagonist Featuring a Facile Thiazolo[5,4-d]pyrimidine Formation
Author:
Affiliation:
1. Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 3210 Merryfield Row, San Diego, California 92121, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op1002984
Reference25 articles.
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3. Analgesic potential of TRPV1 antagonists
4. Branstetter, B. J.; Breitenbucher, J. G.; Lebsack, A. D.; Liu, J.; Rech, J. C.; Xiao, W.U.S. Patent 20090156599, 2009, CAN 151:56868.
5. Novel thienopyrimidine and thiazolopyrimidine kinase inhibitors with activity against Tie-2 in vitro and in vivo
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