Evolution of Potent and Stable Placental-Growth-Factor-1-Targeting CovX-Bodies from Phage Display Peptide Discovery-Reference-Cited by-同舟云学术

Evolution of Potent and Stable Placental-Growth-Factor-1-Targeting CovX-Bodies from Phage Display Peptide Discovery

Published:2011-01-31 Issue:5 Volume:54 Page:1256-1265
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bower Kristen E.¹,Lam Son N.¹,Oates Bryan D.¹,del Rosario Joselyn R.¹,Corner Emily¹,Osothprarop Trina F.¹,Kinhikar Arvind G.¹,Hoye Julie A.¹,Preston R. Ryan¹,Murphy Robert E.¹,Campbell Lioudmila A.¹,Huang Hanhua¹,Jimenez Judith¹,Cao Xia¹,Chen Gang¹,Ainekulu Zemeda W.¹,Datt Aakash B.¹,Levin Nancy J.¹,Doppalapudi Venkata R.¹,Pirie-Shepherd Steven R.¹,Bradshaw Curt¹,Woodnutt Gary¹,Lappe Rodney W.¹

Affiliation:

1. CovX Research, Pfizer, Inc., 9381 Judicial Drive, Suite 200, San Diego, California 92121, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101226k

Reference22 articles.

1. Discovering and improving novel peptide therapeutics

2. Structure and function of immunoglobulins

3. First-in-human dose escalation safety and pharmacokinetic (PK) trial of a novel intravenous (IV) thrombospondin-1 (TSP-1) mimetic humanized monoclonal CovX Body (CVX-045) in patients (pts) with advanced solid tumors

4. FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?

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