Carboxylesterase-Mediated Transesterification of Meperidine (Demerol) and Methylphenidate (Ritalin) in the Presence of [2H6]Ethanol: Preliminary in Vitro Findings Using a Rat Liver Preparation-Reference-Cited by-同舟云学术

Carboxylesterase-Mediated Transesterification of Meperidine (Demerol) and Methylphenidate (Ritalin) in the Presence of [2H6]Ethanol: Preliminary in Vitro Findings Using a Rat Liver Preparation

Published:1997-12 Issue:12 Volume:86 Page:1494-1496
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Bourland James A.,Martin Debra K.,Mayersohn Michael

Publisher

American Geophysical Union (AGU)

Subject

Pharmaceutical Science

Reference15 articles.

1. Clinical significance of esterases in man;Williams;Clin. Pharmocokinet.,1985

2. Human liver cocaine esterases: Ethanol mediated formation of ethylcocaine;Dean;FASEB J.,1991

3. Purification and characterization of a human liver cocaine carboxylesterase that catalyzes the production ofbenzoylecgonine and the formation of cocaethylene from alcohol and cocaine;Brzenzinski;Biochem. Pharmacol.,1994

4. Enzymatic basis for the transesterification of cocaine in the presence of ethanol: evidence for participation of microsomal carboxylesterases;Boyer;J. Pharmacol. Exp. Ther.,1992

5. Cocaethylene: A unique cocaine metabolite displays high affinity for the dopamine transporter;Hearn;J. Neurochem.,1991

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