A Rapid Computational Method for Lead Evolution: Description and Application to α1-Adrenergic Antagonists-Reference-Cited by-同舟云学术

A Rapid Computational Method for Lead Evolution: Description and Application to α1-Adrenergic Antagonists

Published:2000-06-21 Issue:14 Volume:43 Page:2770-2774
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bradley Erin K.¹,Beroza Paul¹,Penzotti Julie E.¹,Grootenhuis Peter D. J.¹,Spellmeyer David C.¹,Miller Jennifer L.¹

Affiliation:

1. Molecular Design Group, CombiChem, Inc., 1804 Embarcadero Road, Suite 201, Palo Alto, California 94303, and Molecular Design Group, CombiChem, Inc., 4570 Executive Drive, Suite 400, San Diego, California 92121

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm990578n

Reference46 articles.

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2. Flexibases: A way to enhance the use of molecular docking methods

3. Rational Combinatorial Library Design. 1. Focus-2D: A New Approach to the Design of Targeted Combinatorial Chemical Libraries

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