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Codon Compression Algorithms for Saturation Mutagenesis

Published:2014-10-30 Issue:5 Volume:4 Page:604-614
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Pines Gur¹,Pines Assaf,Garst Andrew D.¹,Zeitoun Ramsey I.¹,Lynch Sean A.¹²,Gill Ryan T.¹

Affiliation:

1. Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, Colorado 80309, United States

2. Biosciences Center, National Renewable Energy Laboratory, 15013 Denver West Parkway, Golden, Colorado 80401, United States

Funder

Biological and Environmental Research

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/sb500282v

Reference47 articles.

1. A General Method for Saturation Mutagenesis of Cloned DNA Fragments

2. Exploring and designing protein function with restricted diversity

3. A 5000-Fold Increase in the Specificity of a Bacterial Phosphotriesterase for Malathion through Combinatorial Active Site Mutagenesis

4. Evolution of a Pathway to Novel Long-Chain Carotenoids

5. Comparison of random mutagenesis and semi-rational designed libraries for improved cytochrome P450 BM3-catalyzed hydroxylation of small alkanes

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