Design and Synthesis of 4,6-Di-tert-butyl-2,3-dihydro-5-benzofuranols as a Novel Series of Antiatherogenic Antioxidants-Reference-Cited by-同舟云学术

Design and Synthesis of 4,6-Di-tert-butyl-2,3-dihydro-5-benzofuranols as a Novel Series of Antiatherogenic Antioxidants

Published:2003-05-30 Issue:14 Volume:46 Page:3083-3093
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tamura Kunio¹,Kato Yoshiaki¹,Ishikawa Akira¹,Kato Yasuharu¹,Himori Motomu¹,Yoshida Mitsutaka¹,Takashima Yoshiaki¹,Suzuki Tsukasa¹,Kawabe Yoshiki¹,Cynshi Osamu¹,Kodama Tatsuhiko¹,Niki Etsuo¹,Shimizu Makoto¹

Affiliation:

1. Synthetic Technology Research Department, Chugai Pharmaceutical Co., Ltd., 5−5−1 Ukima, Kita-ku, Tokyo 115-8543, Japan, Fuji Gotemba Research Laboratories, Chugai Pharmaceutical Co., Ltd., 1−135 Komakado, Gotemba-shi, Shizuoka 412-8513, Japan, Laboratory for Systems Biology and Medicine, RCAST, The University of Tokyo, 4−6−1 Komaba, Meguro-ku, Tokyo 153-8904, Japan, Human Stress Signal Research Center, AIST, 1−8−31 Midorigaoka, Ikeda-shi, Osaka 563-8577, Japan, and Department of Chemistry for Materials,...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030062a

Reference39 articles.

1. Book ReviewAmbulatory Pediatric Care

2. Low density lipoprotein undergoes oxidative modification in vivo.

3. Role of oxidized low density lipoprotein in atherogenesis.

4. The antioxidant butylated hydroxytoluene protects against atherosclerosis.

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