Asymmetric Synthesis of Tetrahydropyridines via an Organocatalytic One-Pot Multicomponent Michael/Aza-Henry/Cyclization Triple Domino Reaction
Author:
Affiliation:
1. Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074 Aachen, Germany
Funder
European Research Council
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol503024d
Reference40 articles.
1. Spiro-Substituted Piperidines as Neurokinin Receptor Antagonists. I. Design and Synthesis of (.+-.)-N-(2-(3,4-Dichlorophenyl)-4-(spiro(isobenzofuran-1(3H),4'-piperidin)-1'-yl)butyl)-N-methylbenzamide, YM-35375, as a New Lead Compound for Novel Neurokinin Receptor Antagonists.
2. Bacterial Peptide Deformylase Inhibitors: A New Class of Antibacterial Agents
3. Flavor Contribution and Formation of the Intense Roast-Smelling Odorants 2-Propionyl-1-pyrroline and 2-Propionyltetrahydropyridine in Maillard-Type Reactions
4. Formation of Odorants in Maillard Model Systems Based on l-Proline as Affected by pH
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