Synthesis of PPAR Agonist via Asymmetric Hydrogenation of a Cinnamic Acid Derivative and Stereospecific Displacement of (S)-2-Chloropropionic Acid-Reference-Cited by-同舟云学术

Synthesis of PPAR Agonist via Asymmetric Hydrogenation of a Cinnamic Acid Derivative and Stereospecific Displacement of (S)-2-Chloropropionic Acid

Published:2005-04-15 Issue:10 Volume:7 Page:1947-1950
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Houpis Ioannis N.¹,Patterson Lawrence E.¹,Alt Charles A.¹,Rizzo John R.¹,Zhang Tony Y.¹,Haurez Michael¹

Affiliation:

1. Chemical Product Research and Development, Lilly Development Center, Rue Granbonpre 11, B-1348, Mont. St. Guibert, Belgium, and Lilly Technology Center, B-110, Indianapolis, Indiana 46285

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol050367e

Reference14 articles.

1. An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

2. (a) Haigh, D.; Birrell, H. C.; Cantello, B. C. C.; Eggleston, D. S.; Haltiwanger, R. C.; Hindley, R. M.; Ramaswamy, A.; Stevens, N. C.Tetrahedron: Asymmetry1999,10, 1353.

3. Identification of a series of oxadiazole-substituted α-isopropoxy phenylpropanoic acids with activity on PPARα, PPARγ, and PPARδ

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