Alkylation of Phenylglycinol-Derived Oxazolopiperidone Lactams. Enantioselective Synthesis of β-Substituted Piperidines

Author:

Amat Mercedes1,Escolano Carmen1,Lozano Oscar1,Gómez-Esqué Arantxa1,Griera Rosa1,Molins Elies1,Bosch Joan1

Affiliation:

1. Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, 08028-Barcelona, Spain, and Institut de Ciència de Materials (CSIC), Campus UAB, 08193-Cerdanyola, Spain

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference67 articles.

1. Strunz, G. M.; Findlay, J. A. InThe Alkaloids; Brossi, A., Ed.; Academic Press:  London, 1985; Vol. 26, pp 89−183. (b) Takahata, H.; Momose, T. InThe Alkaloids; Cordell, G. A., Ed.; Academic Press:  San Diego, CA, 1993; Vol. 44, pp 189−256. (c) Ohmiya, S.; Saito, K.; Murakoshi, I. InTheAlkaloids; Cordell, G. A., Ed.; Academic Press:  San Diego, 1995; Vol. 47, pp 1−114. (d) Schneider, M. J. InAlkaloids:  Chemical andBiological Perpectives; Pelletier, S. W., Ed; Pergamon:  Oxford, U.K., 1996; Vol. 10, pp 155−299. (e) Andersen, R. J.; Van Soest, R. W. M.; Kong, F. InAlkaloids:  Chemical and Biological Perpectives; Pelletier, S. W., Ed; Pergamon:  Oxford, U.K., 1996; Vol. 10, pp 301−355. (f) Daly, J. W.; Garraffo, H. M.; Spande, T. F. InAlkaloids:  Chemical and BiologicalPerspectives; Pelletier, S. W., Ed.; Pergamon Press:  New York, 1999; Vol. 13, pp 1−161. (g) Watson, P. S.; Jiang, B.; Scott, B.Org. Lett.2000,2, 3679. (h) Michael, J. P.Nat. Prod. Rep.2005,22, 603−626 and previous reviews in this series.

2. (c) Cossy, J.; Vogel, P. InStudies in Natural Products Chemistry.Stereoselective Synthesis(Part H); Atta-ur-Rahman, Ed.; Elsevier:  Amsterdam, 1993; Vol. 12, pp 275−363.

3. (d) Angle, S. R.; Breitenbucher, J. G. InStudies in Natural Products Chemistry(Part J); Atta-ur-Rahman, Ed.; Elsevier:  Amsterdam, The Netherlands, 1995; Vol. 16, pp 453−502.

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