Identification of SR3335 (ML-176): A Synthetic RORα Selective Inverse Agonist-Reference-Cited by-同舟云学术

Identification of SR3335 (ML-176): A Synthetic RORα Selective Inverse Agonist

Published:2010-12-06 Issue:3 Volume:6 Page:218-222
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Kumar Naresh¹,Kojetin Douglas J.¹,Solt Laura A.¹,Kumar K. Ganesh¹,Nuhant Philippe¹,Duckett Derek R.¹,Cameron Michael D.¹,Butler Andrew A.¹,Roush William R.¹,Griffin Patrick R.¹,Burris Thomas P.¹

Affiliation:

1. The Scripps Research Institute, Jupiter, Florida 33458, United States

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb1002762

Reference20 articles.

2. Ligand regulation of retinoic acid receptor-related orphan receptors: implications for development of novel therapeutics

3. Crystal Structure of the Human RORα Ligand Binding Domain in Complex with Cholesterol Sulfate at 2.2 Å

4. X-Ray Structure of the hRORα LBD at 1.63 Å

5. Modulation of Retinoic Acid Receptor-related Orphan Receptor α and γ Activity by 7-Oxygenated Sterol Ligands

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