1. Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, TR-06100 Ankara, Turkey, Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, and Marine Science Institute, University of the Philippines, Diliman, Quezon City 1101, Philippines cireland@deans.pharm.utah.edu.