Interactions of Conformationally Biased North and South 2‘-Fluoro-2‘,3‘-dideoxynucleoside 5‘-Triphosphates with the Active Site of HIV-1 Reverse Transcriptase

Author:

Mu Lan1,Sarafianos Stefan G.1,Nicklaus Marc C.1,Russ Pamela1,Siddiqui Maqbool A.1,Ford Harry1,Mitsuya Hiroaki1,Le Richard1,Kodama Eiichi1,Meier Chris1,Knispel Tina1,Anderson Lynne1,Barchi Joseph J.1,Marquez Victor E.1

Affiliation:

1. Laboratory of Medicinal Chemistry, Division of Basic Sciences, and Experimental Retrovirology Section, Medicine Branch, Division of Clinical Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, and Center for Advanced Biotechnology and Medicine and Rutgers University Chemistry Department, 679 Hoes Lane Piscataway, New Jersey 08854, and Institute of Organic Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, D-20146 Hamburg, Germany

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

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