Interchain Disulfide Bonding in Human IgG2 Antibodies Probed by Site-Directed Mutagenesis-Reference-Cited by-同舟云学术

Interchain Disulfide Bonding in Human IgG2 Antibodies Probed by Site-Directed Mutagenesis

Published:2009-04-15 Issue:17 Volume:48 Page:3755-3766
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Allen Martin J.¹,Guo Amy¹,Martinez Theresa¹,Han Mei¹,Flynn Gregory C.¹,Wypych Jette¹,Liu Yaoqing Diana¹,Shen Wenyan D.¹,Dillon Thomas M.¹,Vezina Christopher¹,Balland Alain¹

Affiliation:

1. Process and Product Development, Amgen, Inc., Seattle, Washington 98119

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi8022174

Reference34 articles.

1. Isotype selection in antibody engineering

2. Immunoglobulins: Structural Studies of Immunoglobulin G

3. IgG4 breaking the rules

4. Intrachain disulfide bond in the core hinge region of human IgG4

5. The inter-heavy chain disulfide bonds of IgG4 are in equilibrium with intra-chain disulfide bonds

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