α-Aryl-N-alkyl Nitrones, as Potential Agents for Stroke Treatment: Synthesis, Theoretical Calculations, Antioxidant, Anti-inflammatory, Neuroprotective, and Brain–Blood Barrier Permeability Properties-Reference-Cited by-同舟云学术

α-Aryl-N-alkyl Nitrones, as Potential Agents for Stroke Treatment: Synthesis, Theoretical Calculations, Antioxidant, Anti-inflammatory, Neuroprotective, and Brain–Blood Barrier Permeability Properties

Published:2011-12-21 Issue:1 Volume:55 Page:153-168
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chioua Mourad¹,Sucunza David¹,Soriano Elena¹,Hadjipavlou-Litina Dimitra²,Alcázar Alberto³,Ayuso Irene³,Oset-Gasque María Jesús⁴⁵,González María Pilar⁴,Monjas Leticia⁶,Rodríguez-Franco María Isabel⁶,Marco-Contelles José¹,Samadi Abdelouahid¹

Affiliation:

1. Laboratorio de Radicales Libres y Química Computacional, Instituto de Química Orgánica General (CSIC), Juan de la Cierva, 3, 28006-Madrid, Spain

2. Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece

3. Departamento Investigación, IRYCIS, Hospital Ramón y Cajal, Madrid, Spain

4. Departamento de Bioquímica y Biología Molecular II, Facultad de Farmacia, Universidad Complutense de Madrid (UCM), 28040 Madrid, Spain

5. Instituto Universitario de Investigación en Neuroquímica (IUIN), Universidad Complutense de Madrid (UCM), 28040 Madrid, Spain

6. Instituto de Química Médica (IQM-CSIC), Juan de la Cierva, 3, 28006-Madrid, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201105a

Reference77 articles.

1. The complexity of neurobiological processes in acute ischemic stroke

2. Nitrones as therapeutics

3. Neuroprotective Effects of a Novel Nitrone, NXY-059, after Transient Focal Cerebral Ischemia in the Rat

4. Evidence for the Efficacy of NXY-059 in Experimental Focal Cerebral Ischaemia Is Confounded by Study Quality

Cited by 63 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Exploration of Synthetic Potential of Quinoline‐3‐Carbaldehydes;European Journal of Organic Chemistry;2024-09-05

2. 1‐Oxa‐2,6‐Diazaspiro[3.3]heptane as a New Potential Piperazine Bioisostere – Flow‐Assisted Preparation and Derivatisation by Strain‐Release of Azabicyclo[1.1.0]butanes;Advanced Synthesis & Catalysis;2024-08-23

3. α-Phenyl-N-tert-Butylnitrone and Analogous α-Aryl-N-alkylnitrones as Neuroprotective Antioxidant Agents for Stroke;Antioxidants;2024-04-07

4. A computational investigation on the photochemistry of the popular spin‐trap agent N‐tert‐butyl‐α‐phenylnitrone (PBN) and thermal isomerization pathways of its photoproduct oxaziridine;International Journal of Quantum Chemistry;2024-04-04

5. Synthesis, antioxidant and neuroprotective analysis of diversely functionalized α-aryl-N-alkyl nitrones as potential agents for ischemic stroke therapy;European Journal of Medicinal Chemistry;2024-02