Discovery of Potent and Selective Benzothiazole Hydrazone Inhibitors of Bcl-XL-Reference-Cited by-同舟云学术

Discovery of Potent and Selective Benzothiazole Hydrazone Inhibitors of Bcl-XL

Published:2013-06-26 Issue:13 Volume:56 Page:5514-5540
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sleebs Brad E.¹²,Kersten Wilhemus J. A.¹²,Kulasegaram Sanji¹²,Nikolakopoulos George¹²,Hatzis Effie¹²,Moss Rebecca M.¹²,Parisot John P.¹²,Yang Hong¹²,Czabotar Peter E.¹²,Fairlie W. Douglas¹²,Lee Erinna F.¹²,Adams Jerry M.¹²,Chen Lin¹²,van Delft Mark F.¹²,Lowes Kym N.¹²,Wei Andrew¹²,Huang David C.S.¹²,Colman Peter M.¹²,Street Ian P.¹²,Baell Jonathan B.¹²,Watson Keith¹²,Lessene Guillaume¹²

Affiliation:

1. The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville VIC-3052, Australia

2. Department of Medical Biology, The University of Melbourne, Parkville VIC-3010, Australia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400556w

Reference53 articles.

1. Killing cancer cells by flipping the Bcl-2/Bax switch

2. Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases