Synthesis and Evaluation of Quinazolines as Inhibitors of the Bacterial Cell Division Protein FtsZ

Author:

Nepomuceno Gabriella M.1,Chan Katie M.1,Huynh Valerie1,Martin Kevin S.1,Moore Jared T.1,O’Brien Terrence E.1,Pollo Luiz A. E.1,Sarabia Francisco J.1,Tadeus Clarissa1,Yao Zi1,Anderson David E.1,Ames James B.1,Shaw Jared T.1

Affiliation:

1. University of California, Davis, One Shields Avenue, Davis, California 95616, United States

Funder

National Institute of Allergy and Infectious Diseases

Alfred P. Sloan Foundation

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Arnold and Mabel Beckman Foundation

U.S. Department of Education

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference36 articles.

1. Resistance to Antibiotics: Are We in the Post-Antibiotic Era?

2. Antibiotic resistance threats in the United States, 2013.http://www.cdc.gov/drugresistance/threat-report-2013/index.html(accessed November 18, 2014).

3. The quinolones: decades of development and use

4. The fluoroquinolone antibacterials: past, present and future perspectives

5. Bacterial cell division as a target for new antibiotics

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