5-Imino-1,2,4-Thiadiazoles: First Small Molecules As Substrate Competitive Inhibitors of Glycogen Synthase Kinase 3-Reference-Cited by-同舟云学术

5-Imino-1,2,4-Thiadiazoles: First Small Molecules As Substrate Competitive Inhibitors of Glycogen Synthase Kinase 3

Published:2012-02-03 Issue:4 Volume:55 Page:1645-1661
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Palomo Valle¹,Perez Daniel I.¹,Perez Concepcion¹,Morales-Garcia Jose A.²,Soteras Ignacio¹,Alonso-Gil Sandra²,Encinas Arantxa¹,Castro Ana¹,Campillo Nuria E.¹,Perez-Castillo Ana²,Gil Carmen¹,Martinez Ana¹

Affiliation:

1. Instituto de Química Médica-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain

2. Instituto de Investigaciones Biomédicas (CSIC-UAM) and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Arturo Duperier 4, 28029 Madrid, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201463v

Reference52 articles.

1. Separation and Characterisation of Glycogen Synthase Kinase 3,Glycogen Synthase Kinase 4 and Glycogen Synthase Kinase 5 from Rabbit Skeletal Muscle

2. Glycogen Synthase Kinase 3 (GSK-3) and Its Inhibitors

3. Glycogen synthase kinase 3: more than a namesake

4. GSK3β: A master switch and a promising target

5. The GSK3 hypothesis of Alzheimer’s disease

Cited by 81 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of new antimicrobial thiophene derivatives with activity against drug-resistant Gram negative-bacteria;Frontiers in Pharmacology;2024-08-20

2. Scaffold hopping for discovery of N, N-dibenzylcinnamamide (DBCA) derivatives as novel allosteric GSK-3β inhibitors: Design, synthesis and anti-inflammatory evaluation;Results in Chemistry;2024-06

3. Emerging phosphodiesterase inhibitors for treatment of neurodegenerative diseases;Medicinal Research Reviews;2024-01-27

4. Glycogen Synthase Kinase-3β Inhibitor VP3.15 Ameliorates Neurogenesis, Neuronal Loss and Cognitive Impairment in a Model of Germinal Matrix-intraventricular Hemorrhage of the Preterm Newborn;Translational Stroke Research;2024-01-17

5. Directed evolution of Escherichia coli surface-displayed Vitreoscilla hemoglobin as an artificial metalloenzyme for the synthesis of 5-imino-1,2,4-thiadiazoles;Chemical Science;2024