Design and Synthesis of a Novel Series of N-Alkyl Isatin Acylhydrazone Derivatives that Act as Selective Cannabinoid Receptor 2 Agonists for the Treatment of Neuropathic Pain-Reference-Cited by-同舟云学术

Design and Synthesis of a Novel Series of N-Alkyl Isatin Acylhydrazone Derivatives that Act as Selective Cannabinoid Receptor 2 Agonists for the Treatment of Neuropathic Pain

Published:2008-07-31 Issue:16 Volume:51 Page:4932-4947
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Diaz Philippe¹,Xu Jijun¹,Astruc-Diaz Fanny¹,Pan Hao-Min¹,Brown David L.¹,Naguib Mohamed¹

Affiliation:

1. Department of Anesthesiology and Pain Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm8002203

Reference58 articles.

1. The Epidemiology of Chronic Pain of Predominantly Neuropathic Origin. Results From a General Population Survey

2. Clinical Effectiveness and Cost-Effectiveness of Treatments for Patients With Chronic Pain

3. Emerging drugs in neuropathic pain

4. The antinociceptive effect of Δ9-tetrahydrocannabinol in the arthritic rat involves the CB2 cannabinoid receptor

5. CB2 receptor-mediated antihyperalgesia: possible direct involvement of neural mechanisms

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