Organic Anion-Transporting Polypeptides 1a/1b Control the Hepatic Uptake of Pravastatin in Mice-Reference-Cited by-同舟云学术

Organic Anion-Transporting Polypeptides 1a/1b Control the Hepatic Uptake of Pravastatin in Mice

Published:2012-08-03 Issue:9 Volume:9 Page:2497-2504
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Iusuf Dilek¹,Sparidans Rolf W.²,van Esch Anita¹,Hobbs Mike³,Kenworthy Kathryn E.³,van de Steeg Evita¹,Wagenaar Els¹,Beijnen Jos H.⁴,Schinkel Alfred H.¹

Affiliation:

1. Division of Molecular Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

2. Department of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands

3. Department of Drug Metabolism and Pharmacokinetics, GlaxoSmithkline, Ware, United Kingdom

4. Department of Pharmacy & Pharmacology, Slotervaart Hospital, Amsterdam, The Netherlands

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp300108c

Reference35 articles.

1. Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

2. Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver

3. Impact of OATP transporters on pharmacokinetics

4. Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and SLCO1B1*15+C1007G, by using transient expression systems of HeLa and HEK293 cells

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