Modification of the Aza-Robinson Annulation for the Synthesis of 4-Methyl-Benzo[c]quinolizin-3-ones, Potent Inhibitors of Steroid 5α-Reductase 1
Author:
Affiliation:
1. Dipartimento di Chimica Organica “U. Schiff” and Centro di Studio sulla Chimica e la Struttura dei Composti Eterociclici e loro Applicazioni, C.N.R., Università di Firenze, Via G. Capponi 9, I-50121 Firenze, Italy guarna@chimorg.unifi.it
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo000603t
Reference12 articles.
1. Benzo[c]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1
2. Synthesis of 8-chloro-benzo[ c ]quinolizin-3-ones as potent and selective inhibitors of human steroid 5α-reductase 1
3. Synthesis of benzo[c]quinolizin-3-ones: Selective non-steroidal inhibitors of steroid 5α-reductase 1
4. Pharmacological Options in the Treatment of Benign Prostatic Hyperplasia
5. Steroid 5α-reductase inhibitors in androgen-dependent disorders
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