Polyketide Decarboxylative Chain Termination Preceded by O-Sulfonation in Curacin A Biosynthesis-Reference-Cited by-同舟云学术

Polyketide Decarboxylative Chain Termination Preceded by O-Sulfonation in Curacin A Biosynthesis

Published:2009-10-16 Issue:44 Volume:131 Page:16033-16035
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Gu Liangcai¹,Wang Bo¹,Kulkarni Amol¹,Gehret Jennifer J.¹,Lloyd Kayla R.¹,Gerwick Lena¹,Gerwick William H.¹,Wipf Peter¹,Håkansson Kristina¹,Smith Janet L.¹,Sherman David H.¹

Affiliation:

1. Life Sciences Institute, Department of Medicinal Chemistry, Department of Chemistry, Department of Biological Chemistry, and Department of Microbiology & Immunology, University of Michigan, Ann Arbor, Michigan 48109, Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, and Scripps Institution of Oceanography, University of California at San Diego, La Jolla, California 92093

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja9071578

Reference20 articles.

1. Structure-Activity Analysis of the Interaction of Curacin A, the Potent Colchicine Site Antimitotic Agent, with Tubulin and Effects of Analogs on the Growth of MCF-7 Breast Cancer Cells

2. Biosynthetic Pathway and Gene Cluster Analysis of Curacin A, an Antitubulin Natural Product from the Tropical Marine Cyanobacterium Lyngbya majuscula

3. GNAT-Like Strategy for Polyketide Chain Initiation

4. Metabolic Coupling of Dehydration and Decarboxylation in the Curacin A Pathway: Functional Identification of a Mechanistically Diverse Enzyme Pair

5. Metamorphic enzyme assembly in polyketide diversification

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