Design, Synthesis, and Biological Evaluation of Dual Binding Site Acetylcholinesterase Inhibitors: New Disease-Modifying Agents for Alzheimer's Disease-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of Dual Binding Site Acetylcholinesterase Inhibitors: New Disease-Modifying Agents for Alzheimer's Disease

Published:2005-10-13 Issue:23 Volume:48 Page:7223-7233
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Muñoz-Ruiz Pilar¹,Rubio Laura¹,García-Palomero Esther¹,Dorronsoro Isabel¹,del Monte-Millán María¹,Valenzuela Rita¹,Usán Paola¹,de Austria Celia¹,Bartolini Manuela¹,Andrisano Vincenza¹,Bidon-Chanal Axel¹,Orozco Modesto¹,Luque F. Javier¹,Medina Miguel¹,Martínez Ana¹

Affiliation:

1. Neuropharma, S.A., Avda. de La Industria 52, 28760 Tres Cantos, Madrid, Spain, Department of Pharmaceutical Sciences, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy, Departamento de Fisicoquímica, Facultad de Farmacia, Universidad de Barcelona, Avda. Diagonal 643, 08028 Barcelona, Spain, and Departamento de Bioquímica y Biología Molecular, Facultad de Química, Universidad de Barcelona, Martí i Franqués 1, 08028 Barcelona, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0503289

Reference59 articles.

1. Deciphering the Molecular Basis of Memory Failure in Alzheimer's Disease

2. Alzheimer's Disease: Genes, Proteins, and Therapy

3. Combination Therapy of Donepezil and Vitamin E in Alzheimer Disease

Cited by 206 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis of conjugates of ipidacrine with oxa/azaheterocycles and their potential as agents for the treatment of Alzheimer’s disease;Russian Chemical Bulletin;2024-06

2. Acetylcholinesterase: A Versatile Template to Coin Potent Modulators of Multiple Therapeutic Targets;Accounts of Chemical Research;2024-02-09

3. Combining Experimental and Computational Methods to Produce Conjugates of Anticholinesterase and Antioxidant Pharmacophores with Linker Chemistries Affecting Biological Activities Related to Treatment of Alzheimer’s Disease;Molecules;2024-01-09

4. Conjugates of amiridine and thiouracil derivatives as effective inhibitors of butyrylcholinesterase with the potential to block β‐amyloid aggregation;Archiv der Pharmazie;2023-12-10

5. Synthesis, Antiacetylcholinesterase Activity, and Molecular Dynamics Simulation of Aporphine–benzylpyridinium Conjugates;ACS Medicinal Chemistry Letters;2023-12-08