Characterization of Racemic Species of Chiral Drugs Using Thermal Analysis, Thermodynamic Calculation, and Structural Studies

Author:

Li Z.Jane,Zell Mark T.,Munson Eric J.,Grant David J.W.

Publisher

American Geophysical Union (AGU)

Subject

Pharmaceutical Science

Reference29 articles.

1. Commonly used chiral drugs: a survey;Millership;Chirality,1993

2. Chiral drugs;Stinson;Chem. Eng. News,1995

3. Enantiomers, Racemates and Resolutions;Jacques,1981

4. A homochiral crystal is composed of a single enantiomer, whereas a heterochiral crystal contains both opposite enan-tiomers in the crystal lattice. A racemic conglomerate is an equimolar physical mixture of homochiral crystals of both enantiomers, while a racemic compound and a pseudorace-mate are heterochiral crystals. In a racemic compound, the two opposite enantiomers are paired up in the unit cell of the crystal lattice, whereas in a pseudoracemate the opposite enantiomers are arranged more or less randomly as a solid solution.

5. Chiral discrimination in crystalline enantiomer systems: Facts, interpretations, and speculations;Collet,1995

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3