1. Department of Occupational and Environmental Health, School of Public Health, Wuhan University, Wuhan 430071, China, Graduate Center for Toxicology and Department of Medicine, University of Kentucky, 234 Health Science Research Building, Lexington, Kentucky 40536, and Laboratory of Cancer Signaling and Epigenetics, Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, West Virginia 26505