Melanin-Concentrating Hormone Receptor 1 Antagonists. Synthesis and Structure–Activity Relationships of Novel 3-(Aminomethyl)quinolines-Reference-Cited by-同舟云学术

Melanin-Concentrating Hormone Receptor 1 Antagonists. Synthesis and Structure–Activity Relationships of Novel 3-(Aminomethyl)quinolines

Published:2012-02-22 Issue:5 Volume:55 Page:2353-2366
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kamata Makoto¹,Yamashita Toshiro¹,Imaeda Toshihiro¹,Tanaka Toshio¹,Masada Shinichi¹,Kamaura Masahiro¹,Kasai Shizuo¹,Hara Ryoma¹,Sasaki Shigekazu¹,Takekawa Shiro¹,Asami Asano¹,Kaisho Tomoko¹,Suzuki Nobuhiro¹,Ashina Shuntaro¹,Ogino Hitomi¹,Nakano Yoshihide¹,Nagisa Yasutaka¹,Kato Koki¹,Kato Kaneyoshi¹,Ishihara Yuji¹

Affiliation:

1. Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1 Muraokahigashi, 2-Chome, Fujisawa, Kanagawa 251-8555, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201596h

Reference12 articles.

1. T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist

2. Discovery, synthesis, and structure–activity relationship of 6-aminomethyl-7,8-dihydronaphthalenes as human melanin-concentrating hormone receptor 1 antagonists

3. 5-HT 2C receptor activation decreases appetite and body weight in obese subjects