X-ray Absorption Spectroscopy of an Investigational Anticancer Gallium(III) Drug: Interaction with Serum Proteins, Elemental Distribution Pattern, and Coordination of the Compound in Tissue-Reference-Cited by-同舟云学术

X-ray Absorption Spectroscopy of an Investigational Anticancer Gallium(III) Drug: Interaction with Serum Proteins, Elemental Distribution Pattern, and Coordination of the Compound in Tissue

Published:2012-06-05 Issue:11 Volume:55 Page:5601-5613
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hummer Alfred A.¹,Bartel Caroline²,Arion Vladimir B.²,Jakupec Michael A.²,Meyer-Klaucke Wolfram³,Geraki Tina⁴,Quinn Paul D.⁴,Mijovilovich Ana⁵,Keppler Bernhard K.²,Rompel Annette¹

Affiliation:

1. Institut für Biophysikalische Chemie, Universität Wien, Althanstraße 14, 1090 Wien, Austria

2. Institut für Anorganische Chemie, Universität Wien, Währinger Straße 42, 1090 Wien, Austria

3. European Molecular Biology Laboratory Hamburg, Notkestraße 85, 22603 Hamburg, Germany

4. Diamond Light Source, Harwell Campus, Didcot OX11 0DE, United Kingdom

5. Inorganic Chemistry and Catalysis Group, Debye Institute for Nanomaterials Science, Utrecht University, Universiteitsweg 99, 3584 CG Utrecht, The Netherlands

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3005459

Reference56 articles.

1. X-ray Crystal Structure of Gallium Tris- (8-hydroxyquinoline): Intermolecular π−π Stacking Interactions in the Solid State

2. Early results from a phase I study on orally administered tris(8-quinolinolato)gallium(III) (FFC11, KP46) in patients with solid tumors ? a CESAR study (Central European Society for Anticancer Drug Research ? EW

3. Antitumor Activity and Toxicity of Salts of Inorganic Group IIIa Metals: Aluminum, Gallium, Indium, and Thallium

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