Inhibition of the Antibacterial Target UDP-(3-O-acyl)-N-acetylglucosamine Deacetylase (LpxC): Isoxazoline Zinc Amidase Inhibitors Bearing Diverse Metal Binding Groups-Reference-Cited by-同舟云学术

Inhibition of the Antibacterial Target UDP-(3-O-acyl)-N-acetylglucosamine Deacetylase (LpxC): Isoxazoline Zinc Amidase Inhibitors Bearing Diverse Metal Binding Groups

Published:2002-08-20 Issue:19 Volume:45 Page:4359-4370
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pirrung Michael C.¹,Tumey L. Nathan¹,Raetz Christian R. H.¹,Jackman Jane E.¹,Snehalatha Karnem¹,McClerren Amanda L.¹,Fierke Carol A.¹,Gantt Stephanie L.¹,Rusche Kristin M.¹

Affiliation:

1. Department of Chemistry, Levine Science Research Center, Box 90317, Duke University, Durham, North Carolina 27708-0317, Department of Biochemistry, Box 3711, Duke University Medical Center, Durham, North Carolina 27710, and Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109-1055

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020183v

Reference41 articles.

1. Resisting resistance: new chemical strategies for battling superbugs

2. An Antibiotic Cloaked by Its Own Resistance Enzyme

3. Funding Crunch Hobbles Antibiotic Resistance Research

Cited by 115 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. LpxC inhibition: Potential and opportunities with carbohydrate scaffolds;Carbohydrate Research;2024-03

2. Synthesis of oxazolines through a Pd-catalyzed alkyne-enabled C N activation of oxazolidines;Tetrahedron Letters;2024-01

3. Novel Hydroxamic Acids Containing Aryl-Substituted 1,2,4- or 1,3,4-Oxadiazole Backbones and an Investigation of Their Antibiotic Potentiation Activity;International Journal of Molecular Sciences;2023-12-20

4. Diastereoselective and Enantioselective Synthesis of Multi‐Functionalized Isoxazoline‐N‐Oxides through Asymmetric [4+1] Annulations;European Journal of Organic Chemistry;2023-06-27

5. Small molecule LpxC inhibitors against gram-negative bacteria: Advances and future perspectives;European Journal of Medicinal Chemistry;2023-05