A Pressure Test to Make 10 Molecules in 90 Days: External Evaluation of Methods to Engineer Biology

Author:

Casini Arturo12,Chang Fang-Yuan13,Eluere Raissa12,King Andrew M.13,Young Eric M.13,Dudley Quentin M.14,Karim Ashty14,Pratt Katelin12,Bristol Cassandra12,Forget Anthony123,Ghodasara Amar3,Warden-Rothman Robert13,Gan Rui14,Cristofaro Alexander13,Borujeni Amin Espah13,Ryu Min-Hyung3,Li Jian4,Kwon Yong-Chan4,Wang He4,Tatsis Evangelos5,Rodriguez-Lopez Carlos5,O’Connor Sarah5,Medema Marnix H.6,Fischbach Michael A.17,Jewett Michael C.14,Voigt Christopher123ORCID,Gordon D. Benjamin123

Affiliation:

1. The Foundry, 75 Ames Street, Cambridge, Massachusetts 02142, United States

2. Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, United States

3. Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States,

4. Department of Chemical and Biological Engineering, Center for Synthetic Biology, Northwestern University, Evanston, Illinois 60208, United States

5. Department of Biological Chemistry, John Innes Centre, Norwich NR4 7UH, United Kingdom

6. Bioinformatics Group, Wageningen University, Wageningen 6708 PB, The Netherlands

7. Department of Bioengineering and Chemistry, Engineering & Medicine for Human Health, Stanford University, Stanford, California 94305, United States

Funder

Novartis

Defense Advanced Research Projects Agency

Banting Research Foundation

National Science Foundation

DSM

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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