A General Strategy for Site-Selective Incorporation of Deuterium and Tritium into Pyridines, Diazines, and Pharmaceuticals
Author:
Affiliation:
1. Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, United States
2. Department of Process Research & Development, MRL, Merck Sharp & Dohme Corp., Rahway, New Jersey 07065, United States
Funder
Colorado State University
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/jacs.7b11710
Reference37 articles.
1. Radiotracers in Drug Development
2. Use of Radiolabeled Compounds in Drug Metabolism and Pharmacokinetic Studies
3. The Use of Radiolabeled Compounds for ADME Studies in Discovery and Exploratory Development
4. Chapter 25 The Use of Isotopically Labeled Compounds in Drug Discovery
5. Tritium: a coming of age for drug discovery and development ADME studies
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