Synthesis of (2<i>R</i>,4<i>S</i>)-4-Amino-5-hydroxybicyclo[3.1.1]heptane-2-carboxylic Acid via an Asymmetric Intramolecular Mannich Reaction-Reference-Cited by-同舟云学术

Synthesis of (2R,4S)-4-Amino-5-hydroxybicyclo[3.1.1]heptane-2-carboxylic Acid via an Asymmetric Intramolecular Mannich Reaction

Published:2024-06-10 Issue:12 Volume:89 Page:9110-9117
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Dukes Adrian O.¹,Weerawarna Pathum M.²^ORCID,Devitt Allison N.¹^ORCID,Silverman Richard B.¹^ORCID

Affiliation:

1. Departments of Chemistry and Molecular Biosciences, Chemistry of Life Processes Institute, and Center for Developmental Therapeutics, Northwestern University, Evanston, Illinois 60208, United States

2. Division of Clinical Pharmacology, School of Medicine, Indiana University, Indianapolis, Indiana 46202, United States

Funder

National Cancer Institute

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.4c00781

Reference45 articles.

1. Rational Optimization of Mechanism-Based Inhibitors through Determination of the Microscopic Rate Constants of Inactivation

2. The resurgence of covalent drugs

3. Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine 1 1 1Edited by R. Huber

4. A novel strategy for the treatment of cocaine addiction

5. Effect of the convulsive agent 3-mercaptopropionic acid on the levels of GABA, other amino acids and glutamate decarboxylase in different regions of the rat brain

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