Synthesis of Differentially Protected Azatryptophan Analogs via Pd2(dba)3/XPhos Catalyzed Negishi Coupling of N-Ts Azaindole Halides with Zinc Derivative from Fmoc-Protected tert-Butyl (R)-2-Amino-3-iodopropanoate

Author:

Nimje Roshan Y1,Vytla Devaiah1,Kuppusamy Prakasam1,Velayuthaperumal Rajeswari1,Jarugu Lokesh Babu1,Reddy China Anki1,Chikkananjaiah Nanjundaswamy Kanikahalli1,Rampulla Richard A.2,Cavallaro Cullen L.2,Li Jianqing3ORCID,Mathur Arvind2,Gupta Anuradha1ORCID,Roy Amrita1ORCID

Affiliation:

1. Department of Discovery Synthesis, Biocon Bristol-Myers Squibb R&D Center, Syngene International Ltd., Biocon Park, Plot No. 2 and 3, Bommasandra-Jigani Road, Bangalore-560 100, India

2. Small Molecule Drug Discovery, Bristol-Myers Squibb Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-4000, United States

3. Small Molecule Drug Discovery, Bristol-Myers Squibb Research and Development, 100 Binney Street, Cambridge, Massachusetts 02142, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

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