Total Synthesis of Sekothrixide Strategically Utilizing Regioselective Coupling of TMS-Protected Epoxy sec-Alcohol with Gilman Reagent-Reference-Cited by-同舟云学术

Total Synthesis of Sekothrixide Strategically Utilizing Regioselective Coupling of TMS-Protected Epoxy sec-Alcohol with Gilman Reagent

Published:2019-01-04 Issue:3 Volume:84 Page:1553-1562
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Katsumi Daisuke¹,Nakasone Kazuki¹,Terayama Naoki¹,Yasui Eiko¹²,Mizukami Megumi³,Miyashita Masaaki¹,Nagumo Shinji¹²^ORCID

Affiliation:

1. Department of Applied Chemistry, Kogakuin University, Nakano 2665-1, Hachioji, Tokyo 192-0015, Japan

2. Department of Chemistry and Life Science, Kogakuin University, Nakano 2665-1, Hachioji, Tokyo 192-0015, Japan

3. Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Hokkaido University of Science, Maeda 7-15-4-1, Teine, Sapporo, Hokkaido 006-8585, Japan

Funder

Ministry of Education, Culture, Sports, Science and Technology

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.8b03006

Reference28 articles.

1. Small-molecule inhibitors of protein–protein interactions: progressing towards the dream

2. Reaching for high-hanging fruit in drug discovery at protein–protein interfaces

3. Chemical modulators working at pharmacological interface of target proteins

4. An architectonic macrolide library based on a C2-symmetric macrodiolide toward pharmaceutical compositions

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