Modular Total Synthesis of Farnesyl Analogues of Cell Wall Precursors Lipid I and II Containing the Staphylococcus aureus Pentaglycine Bridge Modification-Reference-Cited by-同舟云学术

Modular Total Synthesis of Farnesyl Analogues of Cell Wall Precursors Lipid I and II Containing the Staphylococcus aureus Pentaglycine Bridge Modification

Published:2020-06-23 Issue:15 Volume:85 Page:10206-10215
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Wingen Lukas M.¹,Rausch Marvin²³,Schneider Tanja²,Menche Dirk¹^ORCID

Affiliation:

1. Kekulé Institute of Organic Chemistry and Biochemistry, University of Bonn, 53121 Bonn, Germany

2. Institute for Pharmaceutical Microbiology, University Clinic Bonn, University of Bonn, 53115 Bonn, Germany

3. German Center for Infection Research (DZIF), partner site Bonn-Cologne, 53127 Bonn, Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.0c01004

Reference20 articles.

1. Targeting a cell wall biosynthesis hot spot

2. Structural variations of the cell wall precursor lipid II in Gram-positive bacteria — Impact on binding and efficacy of antimicrobial peptides

3. The pentaglycine bridges of Staphylococcus aureus peptidoglycan are essential for cell integrity

4. The First Total Synthesis of Lipid II: The Final Monomeric Intermediate in Bacterial Cell Wall Biosynthesis

5. Lipid II: Total Synthesis of the Bacterial Cell Wall Precursor and Utilization as a Substrate for Glycosyltransfer and Transpeptidation by Penicillin Binding Protein (PBP) 1b of Eschericia coli

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3. Strategies and tactics for the synthesis of lipid I and II and shortened analogues: functional building blocks of bacterial cell wall biosynthesis;Natural Product Reports;2023

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