Enantioselective Total Synthesis of Nitraria Alkaloids: (+)-Nitramine, (+)-Isonitramine, (−)-Isonitramine, and (−)-Sibirine via Asymmetric Phase-Transfer Catalytic α-Allylations of α-Carboxylactams

Author:

Yang Jewon1,Park Yohan2ORCID,Yang Sehun1,Lee Geumwoo1,Ha Min Woo3,Kim Mi-hyun4ORCID,Hong Suckchang1ORCID,Park Hyeung-geun1ORCID

Affiliation:

1. Research Institute of Pharmaceutical Sciences and College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea

2. College of Pharmacy, Inje Institute of Pharmaceutical Sciences and Research, Inje University, 197 Inje-ro, Gimhae, Gyeongnam 50834, Republic of Korea

3. College of Pharmacy, Jeju National University, 102 Jejudaehak-ro Jeju 63243, Republic of Korea

4. College of Pharmacy, Gachon University, 191 Hambakmoero, Yeonsu-gu, Incheon 21936, Republic of Korea

Funder

National Research Foundation of Korea

Seoul National University

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference58 articles.

1. aManske, R. H. F. The Alkaloids. Chemistry and Physiology; Academic Press: New York, 1965; Vol. VIII, p 673.

2. cBrossi, A. The Alkaloids: Chemistry and Pharmacology; Academic Press, 1989; Vol. 35, p 261.

3. dGeoffrey, A. Cordell The Alkaloids: Chemistry and Biology; Elsevier, 2001; Vol. 56, p 8.

4. Enantioselective synthesis of polyzonimine and nitropolyzonamine, spirocyclic compounds from the defensive glands of a millipede, Polyzonium rosalbum

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