Stereoselective Synthesis of a Dipyridyl Transient Receptor Potential Vanilloid-3 (TRPV3) Antagonist-Reference-Cited by-同舟云学术

Stereoselective Synthesis of a Dipyridyl Transient Receptor Potential Vanilloid-3 (TRPV3) Antagonist

Published:2016-11-14 Issue:23 Volume:81 Page:12060-12064
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Voight Eric A.¹,Daanen Jerome F.¹,Schmidt Robert G.¹,Gomtsyan Arthur¹,Dart Michael J.¹,Kym Philip R.¹

Affiliation:

1. Centralized Lead Optimization − Discovery Chemistry & Technology, AbbVie, Inc., 1 N Waukegan Rd, North Chicago, Illinois 60064, United States

Funder

AbbVie

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.6b02443

Reference19 articles.

1. Overcoming obstacles to developing new analgesics

2. TRP Channels and Pain

3. Targeting Pain-evoking Transient Receptor Potential Channels for the Treatment of Pain

4. Targeting TRPV3 for the Development of Novel Analgesics

5. aBayburt, E. K.; Clapham, B.; Cox, P. B.; Daanen, J. F.; Gomtsyan, A.; Kort, M. E.; Kym, P. R.; Voight, E. A.; Schmidt, R. G.; Dart, M. J.; Gfesser, G.Methanol derivatives as trpv3 modulators. Patent WO2013062964.

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