Debenzylative Cycloetherification as a Synthetic Tool in the Diastereoselective Synthesis of 3,6-Disubstituted Hexahydro-2H-furo[3,2-b]pyrroles, PDE1 Enzyme Inhibitors with an Antiproliferative Effect on Melanoma Cells-Reference-Cited by-同舟云学术

Debenzylative Cycloetherification as a Synthetic Tool in the Diastereoselective Synthesis of 3,6-Disubstituted Hexahydro-2H-furo[3,2-b]pyrroles, PDE1 Enzyme Inhibitors with an Antiproliferative Effect on Melanoma Cells

Published:2020-04-06 Issue:9 Volume:85 Page:5941-5951
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Castán Alejandro¹,Badorrey Ramón¹,Díez José A.¹,Christoffersen Claus T.²,Rasmussen Lars K.²,Kehler Jan²,Köhler Ralf³⁴,Gálvez José A.¹,Díaz-de-Villegas María D.¹^ORCID

Affiliation:

1. Departamento de Quı́mica Orgánica, Instituto de Sı́ntesis Quı́mica y Catálisis Homogénea (ISQCH), CSIC−Universidad de Zaragoza, Pedro Cerbuna 12, 50009 Zaragoza, Spain

2. H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark

3. Aragon Institute of Health Sciences & IIS, 50009 Zaragoza, Spain

4. Aragon Agency for Research and Development (ARAID), 50018 Zaragoza, Spain

Funder

Government of Aragon

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.0c00276

Reference46 articles.