Synthesis of an Aminooxy Derivative of the GM3 Antigen and Its Application in Oxime Ligation
Author:
Affiliation:
1. Department of Chemistry and Biochemistry and School of Green Chemistry and Engineering, University of Toledo, 2801 West Bancroft Street, Toledo, Ohio 43606, United States
Funder
National Cancer Institute
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.0c00320
Reference41 articles.
1. The Velocity of Hydrolysis of Stereoisomeric Hydrazones and Oximes
2. Hydrolytic Stability of Hydrazones and Oximes
3. Synthesis of glycoimmunogen Tn-Thr-PS A1 via hydrazone bond and stability optimization of PS A1 monosaccharide mimics under vaccine development conditions
4. The Immunogenicity of the Tumor-Associated Antigen Lewisy May Be Suppressed by a Bifunctional Cross-Linker Required for Coupling to a Carrier Protein
5. Significant Impact of Immunogen Design on the Diversity of Antibodies Generated by Carbohydrate-Based Anticancer Vaccine
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