Sustainability Challenges in Peptide Synthesis and Purification: From R&D to Production-Reference-Cited by-同舟云学术

Sustainability Challenges in Peptide Synthesis and Purification: From R&D to Production

Published:2019-03-22 Issue:8 Volume:84 Page:4615-4628
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Isidro-Llobet Albert¹^ORCID,Kenworthy Martin N.²,Mukherjee Subha³,Kopach Michael E.⁴,Wegner Katarzyna⁵,Gallou Fabrice⁶,Smith Austin G.⁷,Roschangar Frank⁸

Affiliation:

1. Medicines Research Centre, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, U.K.

2. Pharmaceutical Technology and Development, AstraZeneca, Silk Road Business Park, Charter Way, Macclesfield SK10 2NA, U.K.

3. Chemical and Synthetic Development, Bristol-Myers Squibb Company, One Squibb Drive, New Brunswick, New Jersey 08903, United States

4. Small Molecule Design and Development, Eli Lilly and Company, 1400 West Raymond Street, Indianapolis, Indiana, United States

5. Active Pharmaceutical Ingredient Development, IPSEN Manufacturing Ireland, Ltd., Blanchardstown Industrial Park, Dublin 15, Ireland

6. Chemical & Analytical Development, Novartis, 4056 Basel, Switzerland

7. Drug Substance Process Development, Amgen, Inc., 1 Amgen Center Drive, Thousand Oaks, California 91320, United States

8. Chemical Development, Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut 06877, United States

Funder

American Chemical Society

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.joc.8b03001

Reference163 articles.

1. https://www.acs.org/content/acs/en/greenchemistry/about.html (accessed March 15, 2019).

2. Introduction of a process mass intensity metric for biologics

3. The Current State of Peptide Drug Discovery: Back to the Future?

4. The greening of peptide synthesis

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