Tandem Amination/Oxetane Ring Opening toward Benzomorpholines
Author:
Affiliation:
1. Janssen Research and Development, 1400 McKean Road, Spring House, Pennsylvania 19477, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.1c02166
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1. Development of Novel Benzomorpholine Class of Diacylglycerol Acyltransferase I Inhibitors
2. 2,6-Difluorobenzamide Inhibitors of Bacterial Cell Division Protein FtsZ: Design, Synthesis, and Structure-Activity Relationships
3. Design, synthesis, and preliminary biological evaluation of 2,3-dihydro-3-hydroxymethyl-1,4-benzoxazine derivatives
4. Design and Optimization of Benzopiperazines as Potent Inhibitors of BET Bromodomains
5. Design, Synthesis, and Structure–Activity and Structure–Pharmacokinetic Relationship Studies of Novel [6,6,5] Tricyclic Fused Oxazolidinones Leading to the Discovery of a Potent, Selective, and Orally Bioavailable FXa Inhibitor
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