Synthesis of 2,4,6-Trisubstituted Pyrimidines through Copper-Catalyzed [4 + 2] Annulation of α,β-Unsaturated Ketoximes with Activated Nitriles
Author:
Affiliation:
1. College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, China
Funder
Natural Science Foundation of Jiangsu Province
National Natural Science Foundation of China
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.3c00687
Reference53 articles.
1. Synthesis of Stable N–H Imines with a Benzo[7,8]indolizine Core and Benzo[7,8]indolizino[1,2-c]quinolines via Copper-Catalyzed Annulation of α,β-Unsaturated O-Acyl Ketoximes with Isoquinolinium N-Ylides
2. Recent progress on discovery and research of aldoxime dehydratases
3. Thioether Ligand-Enabled Cationic Palladium(II)-Catalyzed Electrophilic C–H Arylation of α,β-Unsaturated Oxime Ethers
4. γ-Carboline synthesis enabled by Rh(iii)-catalysed regioselective C–H annulation
5. Copper-Catalyzed Intermolecular [4 + 2] Annulation Enabled by Internal Oxidant-Promoted C(sp3)–H Functionalization: Access to 3-Trifluoromethylated 3-Hydroxy-cyclohexan-1-ones
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